The effect of clary sage oil on staphylococci responsible for wound infections

نویسندگان

  • Monika Sienkiewicz
  • Anna Głowacka
  • Katarzyna Poznańska-Kurowska
  • Andrzej Kaszuba
  • Anna Urbaniak
  • Edward Kowalczyk
چکیده

INTRODUCTION The spreading of bacterial antibiotic resistance among clinical strains of pathogenic bacteria has made investigators to search for other active antibacterial agents which could provide a valuable complement to the existing therapies. AIM To determine the antibacterial activity of clary sage oil (Salvia sclarea L.) against Staphylococcus clinical strains which were isolated from patients with wound infections. MATERIAL AND METHODS A comprehensive evaluation of Staphylococcus clinical strain resistance to antibiotics was performed. The constituents of clary sage oil were assayed by GC-FID-MS analysis. The minimal inhibitory concentration (MIC) of the tested essential oil against staphylococci by the micro-dilution broth method was determined. RESULTS The clary sage oil was active against Staphylococcus aureus, S. epidermidis and S. xylosus with MIC values ranging from 3.75 to 7.00 µl/ml. CONCLUSIONS The results of the in vitro tests encourage to use formulations containing sage oil as the active natural antimicrobial agent. Because of its antimicrobial properties clary sage oil may be applied to treat wounds and skin infections.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Insecticidal Effect of Clary Sage (Salvia sclarea) Essential oil Against Callosobruchus maculatus (Col: Bruchidae) and Tribolium confusum (Col: Tenebrionidae)

Background: Nowadays stored–product insect pests are controlled by pesticides and chemical fumigant compounds. The continueous use of chemical pesticides is harmful for non–target creatures specially humans and other mammals. Beside they polluted the environment. Objective: Accoring to the studies, the essential oil of Labiatae plants have insecticidal activity against some pests. In this st...

متن کامل

Effects of Irrigation Interval and Nitrogen Amount on Different Clary Sage (Salvia sclarea L.) Characters in Karaj

Salvia sclarea L, is an important medicinal plant that its oil has been evaluated for antioxidant, antibacterial, antifungal, anti-inflammatory, antimalarial, anticholinesterase and antiviral. Yield of plants are influenced by environmental and agricultural management factors such as drought stress and nutrition. Plant nutrition is one of the most important factors that positively influence pla...

متن کامل

Effects of Salvia sclarea on chronic immobilization stress induced endothelial dysfunction in rats

BACKGROUND Although Salvia sclarea (clary sage) is widely used in aromatherapy and has antioxidant and antimicrobial properties, its mechanisms of action remain poorly understood. We therefore assessed whether clary sage is effective in treating endothelial dysfunction induced by chronic immobilization stress in rats. METHODS Rats were intraperitoneally injected with almond oil, clary sage oi...

متن کامل

Isolation and Characterization of Coagulase Positive, Methicillin and Multi-Drug Resistant Staphylococcus and Mammaliicoccus species Isolated from of Wound Patients Attending Federal Medical Centre, Yola, Adamawa State, Nigeria

Background and objective: The treatment of bacterial infections especially of the family Staphylococcaceae is a significant health burden that has led to economic losses, and high morbidity and mortality rates globally. This study aimed at the isolation and characterization of coagulase-positive, methicillin, and multi-drug-resistant Staphylococci isolated from wounds of patients. Methods: Fo...

متن کامل

Identification of Chemical Compounds and Evaluation of Antioxidant and Antimicrobial Properties of Sage (Salvia officinalis L.) Essential Oil at Different Harvest Times

Background and Objectives: Today, the identification and introduction of plant species with medicinal and antimicrobial properties have become considerably important due to the increased use of chemical drugs, spread of microbial resistance to antibiotics, and side effects of drug consumption. Sage (Salvia officinalis L.) is one of the most important medicinal and aromatic plants possessing ant...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 32  شماره 

صفحات  -

تاریخ انتشار 2015